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InChiKey: CUDVHEFYRIWYQD-UHFFFAOYSA-N
KN-62 is a selective antagonist of Ca2+/calmodulin-dependent protein kinase II (CaMKII)
Veiga-Crespo P
Chemical Name: N-(5-(4-((1
InChiKey: STUWGJZDJHPWGZ-LBPRGKRZSA-N
Sorafenib Tosylate - CAS# 475207-59-1 rizine dihydrochloride InChiKey: CUDVHEFYRIWYQD-UHFFFAOYSA-NSorafenib, also known as BAY 43 9006, is a synthetic compound targeting growth signaling and angiogenesis. Sorafenib blocks the enzyme RAF kinase, a critical component of the RAF MEK ERK signaling pathway that controls cell division and proliferation; in addition, sorafenib inhibits the VEGFR 2 PDGFR beta signaling cascade, thereby blocking tumor angiogenesis. Sorafenib was approved in 2005 for use in the treatment of advanced renal cancer. Product
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